Amphetamine was first synthesized back in 1887 by German scientists. However, it took almost fifty years for the drug to be noticed and tested for possible applications. In the late 1920’s they started to test amphetamine as a possible remedy for anything and everything from simple cough to serious health and mental issues. A decade later Benzedrine hit the stores as an over the counter inhaler that was supposed to help nasal congestion. Needless to say, because of the active ingredient of amphetamine this product was used not only by asthmatics and sick people, but also by enthusiasts who was looking for a buzz during the years of the Great Depression and Prohibition. A few years later amphetamine became available in form of a tablet as well.

Following this scientific discovery, in 1919 a stronger and easier to make substance was discovered in Japan. The powder that could dissolve in water had presented a perfect opportunity to develop into injections. This substance was methamphetamine. The ability of the drug to “keep you going” became very handy during the World War II – methamphetamine was extensively used to keep soldiers alert in the line of duty. After the war the substance remained popular among students, athletes, truck drivers and general pubic representatives who wished to prolong their alertness and stay awake for longer.

Up until late 1950s methamphetamine (Methedrine pills) and dextroamphetamine (sold in the form of pills named Dexedrine) were easily available for purchase to public. Soon enough the situation had changed.